Cart
sales@molnova.com
GC7 Sulfate
CAS No. 150417-90-6
GC7 Sulfate( —— )
Catalog No. M32934 CAS No. 150417-90-6
GC7 Sulfate is a potent inhibitor of deoxyhypusine synthase (DHS). Eukaryotic translation initiation factor 5A2 (eIF5A2) is the only known substrate for DHS, so GC7 inhibits the activation of eIF5A2 by inhibiting DHS activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 45 | In Stock |
|
| 10MG | 85 | In Stock |
|
| 25MG | 181 | In Stock |
|
| 50MG | 273 | In Stock |
|
| 100MG | 430 | In Stock |
|
| 500MG | 945 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGC7 Sulfate
-
NoteResearch use only, not for human use.
-
Brief DescriptionGC7 Sulfate is a potent inhibitor of deoxyhypusine synthase (DHS). Eukaryotic translation initiation factor 5A2 (eIF5A2) is the only known substrate for DHS, so GC7 inhibits the activation of eIF5A2 by inhibiting DHS activity.
-
DescriptionGC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAutophagy
-
TargetAutophagy
-
RecptorAutophagy
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number150417-90-6
-
Formula Weight270.35
-
Molecular FormulaC8H22N4O4S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?H2O : 3 mg/mL (11.10 mM)
-
SMILESO=S(=O)(O)O.N=C(N)NCCCCCCCN
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Bandino A, et al. Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients. Cell Oncol (Dordr). 2014 Dec;37(6):387-98.?
molnova catalog
related products
-
Pyronine B
Pyronine B (NSC 44690) is a fluorophore with low relative fluorophore brightness and a small hydrophobic (SH) protein channel inhibitor, which is used for staining of bacteria and mycobacteria and in the spectrophotometric determination of ultra-trace ruthenium.
-
SLLN-15
SLLN-15 (Autophagy inducer SLLN-15) is a potent, orally available inducer of autophagy that selectively activated cytostatic macroautophagy/autophagy in TNBC preclinical models.
-
Sulfalen
Sulfalene is a long-acting sulfonamide antibiotic used for the treatment of chronic bronchitis, urinary tract infections and malaria.
